Publications
A selection of recent BSRC members’ publications are listed below.
A programmatic assessment of dolutegravir adverse events and discontinuations in Uganda
Laker Odongpiny, E. A., Nicol, M., Katana, E., Owori, J., Buzibye, A., Sedan, K., Kesby, M., Holden, M., Owarwo, N., Meya, D., Castelnuovo, B., Sloan, D. J. & Sekaggya, C., 24 Jan 2025, (E-pub ahead of print) In: HIV Medicine. Early View, 14 p.
Research output: Contribution to journal › Article › peer-review
Abnormal plasma/serum magnesium, copper and zinc concentrations associate with the future development of cardiovascular diseases
Lin, B., Alexander, R., Fritzen, R., Mills, S., Stewart, A. J. & McCowan, C., 23 Apr 2025, (Accepted/In press) In: Nutrients.
Research output: Contribution to journal › Article › peer-review
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Sutherland, E., Harding, C. J., du Monceau de Bergendal, T., Florence, G. J., Ackermann, K., Bode, B. E., Synowsky, S., Sundaramoorthy, R. & Melo Czekster, C., 24 Jan 2025, In: Nature Communications. 16, 14 p., 995.
Research output: Contribution to journal › Article › peer-review
CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes
Sun, Y., Kronenberg, N. M., Sethi, S. K., Dash, S. N., Kovalik, M. E., Sempowski, B., Strickland, S., Raina, R., Sperati, C. J., Tian, X., Ishibe, S., Hall, G. & Gather, M. C., 1 Apr 2025, In: American Journal of Physiology - Renal Physiology. 328, 4, p. F578-F595 18 p.
Research output: Contribution to journal › Article › peer-review
Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomiasis
Gruschow, S., Steketee, P. C., Paxton, E., Matthews, K. R., Morrison, L. J., White, M. F. & Grey, F., 17 Mar 2025, In: PLoS Neglected Tropical Diseases. 19, 3, p. 1-17 17 p., e0012937.
Research output: Contribution to journal › Article › peer-review
Competitive behaviors in Serratia marcescens are coordinately regulated by a lifestyle switch frequently inactivated in the clinical environment
Williams, D. J., Hawkins, A., Hernandez, R. E., Mariano, G., Mathers, K., Buchanan, G., Stonier, B. J., Inkster, T., Leanord, A., Chalmers, J. D., Thomson, N. R., Holden, M. T. G. & Coulthurst, S. J., 12 Feb 2025, In: Cell Host & Microbe. 33, 2, p. 252-266.E5 20 p.
Research output: Contribution to journal › Article › peer-review
DNA sensing with whispering gallery mode microlasers
Caixero, S., Dörrenhaus, R., Popczyk, A., Schubert, M., Kath-Schorr, S. & Gather, M. C., 19 Mar 2025, In: Nano Letters. 25, 11, p. 4467–4475
Research output: Contribution to journal › Letter › peer-review
Engineering mechanical resonances of magnetoelectric transducers
Butscher, J. F. & Gather, M. C., 4 Feb 2025, In: Applied Physics Letters. 126, 5, 6 p., 053503.
Research output: Contribution to journal › Article › peer-review
Experimental analysis to quantify inactivation of microorganisms by Far-UVC irradiation in indoor environments
Hiwar, W., Adamson, C. S., Brenner, D. J., Fletcher, L. A., King, M.-F., McQuaid, J. B., Tidswell, E., Noakes, C. J., Wood, K. & Eadie, E., 15 Apr 2025, In: Building and Environment. 274, p. 1-10 10 p., 112734.
Research output: Contribution to journal › Article › peer-review
Exploring the activity of the putative Δ6-desaturase and its role in bloodstream form life-cycle transitions in Trypanosoma brucei
Cerone, M. & Smith, T. K., 18 Feb 2025, In: PLoS Pathogens. 21, 2, p. 1-39 39 p., e1012691.
Research output: Contribution to journal › Article › peer-review
Expression profile of human cytomegalovirus UL111A cmvIL-10 and LAcmvIL-10 transcripts in primary cells and cells from renal transplant recipients
Almeida, G. W. C., Oliveira, M. T., Martines, I. G. L., Fiori, G. C., Nevels, M. M., Groves, I. J., Sinclair, J., Medina-Pestana, J., Sampaio da Silva, R., Nakamura, M., Requião-Moura, L., Poole, E. & Carlan da Silva, M. C., 31 Mar 2025, In: Viruses. 17, 15 p., 501.
Research output: Contribution to journal › Article › peer-review
Genetics of human handedness: microtubules and beyond
Ocklenburg, S., Mundorf, A., Peterburs, J. & Paracchini, S., 1 Feb 2025, (E-pub ahead of print) In: Trends in Genetics.
Research output: Contribution to journal › Review article › peer-review
ISG15-dependent stabilisation of USP18 is necessary but not sufficient to regulate type I interferon signalling in humans
Vasou, A., Nightingale, K., Cetkovská , V., Scheler, J., Bamford, C. G. G., Andrejeva, J., Rowe, J. C., Swatek, K. N., Schwarz-Linek, U., Randall, R. E., McLauchlan, J., Weekes, M. P., Bogunovic, D. & Hughes, D. J., 11 Feb 2025, In: European Journal of Immunology. 55, 2, 16 p., e202451651.
Research output: Contribution to journal › Article › peer-review
Immobilized nucleoside 2-deoxyribosyltransferases from extremophiles for nucleoside biocatalysis
Hernández Martínez, S., Tang, P., Parra-Saldivar, R., Melchor-Martínez, E. & Melo Czekster, C., 14 Jan 2025, In: ACS Omega. 10, 1, p. 1067-1076 10 p.
Research output: Contribution to journal › Article › peer-review
In-cage recombination facilitates the enantioselective organocatalytic [1,2]-rearrangement of allylic ammonium ylides
Hartley, W., Kasten, K., Greenhalgh, M. D., Feoktistova, T., Wise, H., Laddusaw, J., Frost, A. B., Ng, S., Slawin, A. M. Z., Bode, B. E., Cheong, P. & Smith, A. D., 8 Jan 2025, In: Journal of the American Chemical Society. 147, 1, p. 1101-1111 11 p.
Research output: Contribution to journal › Article › peer-review
Investigating the time to blood culture positivity: why does it take so long?
Falconer, K., Hammond, R., Parcell, B. & Gillespie, S. H., 6 Jan 2025, In: Journal of Medical Microbiology. 74, 1, 10 p.
Research output: Contribution to journal › Article
Isoselenourea‐catalyzed enantioselective pyrazolo‐heterocycle synthesis enabled by self‐correcting amide and ester acylation
Prindl, M. I., Westwood, M. T., Goodfellow, A. S., McKay, A. P., Cordes, D. B., Bühl, M. & Smith, A. D., 31 Mar 2025, (E-pub ahead of print) In: Angewandte Chemie International Edition. Early View, 12 p., e202425305.
Research output: Contribution to journal › Article › peer-review
Isothiourea-catalysed enantioselective synthesis of phosphonate-functionalised β-lactones
Platt, F. M., Wang, Y., Cordes, D. B., McKay, A. P., Slawin, A. M. Z., Panchal, H. & Smith, A. D., 6 Mar 2025, (E-pub ahead of print) In: Chemical Science. Advance Articles, 9 p.
Research output: Contribution to journal › Article › peer-review
Kinetic and thermodynamic characterization of human 4-oxo-L-proline reductase catalysis
Pecaver, E., Zickuhr, G. M., Machado, T. F. G., Harrison, D. J. & da Silva, R. G., 18 Feb 2025, In: Biochemistry. 64, 4, p. 860-870 11 p.
Research output: Contribution to journal › Article › peer-review
Live-cell RNA imaging with the inactivated endonuclease Csy4 enables new insights into plant virus transport through plasmodesmata
Burnett, D., Hussein, M., Barr, Z. K., Näther, L. N., Wright, K. M. & Tilsner, J., 9 Apr 2025, In: PLoS Pathogens. 21, 4, p. 1-31 31 p., e1013049.
Research output: Contribution to journal › Article › peer-review
Microrheology of the cumulus-oocyte matrix using optical tweezers
Campugan, C. A., Perrella, C., Lim, M., Tan, T. C. Y., Schartner, E. P., Arita, Y., Bruce, G. D., Mendonca, T., Wright, A. J., Dholakia, K. & Dunning, K. R., 20 Feb 2025, In: JPhys Photonics. 7, 2, 10 p., 025008.
Research output: Contribution to journal › Article › peer-review
Patterns of antibiotic resistance in urinary tract infections before and during the COVID-19 pandemic in Uganda and Tanzania
Silago, V., Keenan, K., Mushi, M. F., Kansiime, C., Asiimwe, B., Sunday, B., Bazira, J., Sandeman, A., Sabiiti, W., Seni, J., Holden, M. T. G., Mshana, S. E. & behalf of the HATUA and CARE Consortia, Apr 2025, In: JAC-Antimicrobial Resistance. 7, 2, p. 1-4 4 p., dlaf038.
Research output: Contribution to journal › Article › peer-review
Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants
Pérez-Sancho, J., Smokvarska, M., Dubois, G., Glavier, M., Sritharan, S., Moraes, T. S., Moreau, H., Dietrich, V., Platre, M. P., Paterlini, A., Li, Z. P., Fouillen, L., Grison, M. S., Cana-Quijada, P., Immel, F., Wattelet, V., Ducros, M., Brocard, L., Chambaud, C. & Luo, Y. & 14 others, , 20 Feb 2025, In: Cell. 188, 4, p. 958-977 20 p.
Research output: Contribution to journal › Article › peer-review
Progressive evolution of Streptococcus equi from Streptococcus equi subsp. zooepidemicus and adaption to equine hosts
Wilson, H. J., Dong, J., van Tonder, A. J., Ruis, C., Lefrancq, N., McGlennon, A., Bustos, C., Frosth, S., Léon, A., Blanchard, A. M., Holden, M., Waller, A. S. & Parkhill, J., 28 Mar 2025, In: Microbial Genomics. 11, 3, p. 1-13 13 p., 001366.
Research output: Contribution to journal › Article › peer-review
Properties of the major Zn2+-binding site of human alpha-fetoprotein, a potential foetal plasma zinc carrier
Lu, J., Hierons, S. J., Arya, S., Fritzen, R., Polepalli, S., Khazaipoul, S., Stewart, A. J. & Blindauer, C. A., 4 Feb 2025, In: Chemical Communications. 61, 10, p. 2099-2102 4 p.
Research output: Contribution to journal › Article › peer-review
Quantitative proteomics identifies plasma protein alterations that associate with metabolic and thrombotic profile changes after bariatric surgery
Ahmed, H., Fernandes, M. F., Abbas, K., Synowsky, S. A., Shirran, S. L., Ajjan, R. A. & Stewart, A. J., May 2025, In: Diabetes, Obesity and Metabolism. 27, 5, p. 2647-2657 11 p.
Research output: Contribution to journal › Article › peer-review
Recombinant production platform for Group A Streptococcus glycoconjugate vaccines
Ajay Castro, S., Passmore, I. J., Ndeh, D., Shaw, H. A., Ruda, A., Burns, K., Thomson, S., Nagar, R., Alagesan, K., Reglinski, M., Lucas, K., Abouelhadid, S., Schwarz-Linek, U., Mawas, F., Widmalm, G., Wren, B. W. & Dorfmueller, H. C., 22 Jan 2025, In: npj Vaccines. 10, p. 1-14 14 p., 16.
Research output: Contribution to journal › Article › peer-review
Resistify: a novel NLR classifier that reveals helitron-associated NLR expansion in Solanaceae
Smith, M., Jones, J. T. & Hein, I., 22 Jan 2025, In: Bioinformatics and Biology Insights. 19, p. 1-9 9 p.
Research output: Contribution to journal › Article › peer-review
Robustness and sensitivity of Gd(III)-Gd(III) double electron electron resonance (DEER) measurements: comparative study of high-frequency EPR spectrometer designs and spin label variants
Mocanu, E. M., Ben-Ishay, Y., Topping, L., Fisher, S. R., Hunter, R. I., Su, X.-C., Butler, S., Smith, G. M., Goldfarb, D. & Lovett, J. E., 3 Jan 2025, (E-pub ahead of print) In: Applied Magnetic Resonance. Early View, 21 p.
Research output: Contribution to journal › Article › peer-review
Safety, bactericidal activity, and pharmacokinetics of the antituberculosis drug candidate BTZ-043 in South Africa (PanACEA-BTZ-043–02): an open-label, dose-expansion, randomised, controlled, phase 1b/2a trial
Heinrich, N., de Jager, V., Dreisbach, J., Gross-Demel, P., Schultz, S., Gerbach, S., Kloss, F., Dawson, R., Narunsky, K., Matt, L., Wildner, L., McHugh, T. D., Fuhr, U., Aldana, B. H., Mouhdad, C., Brake, L. T., Boeree, M. J., Aarnoutse, R. E., Svensson, E. M. & Gong, X. & 4 others, , 7 Jan 2025, (E-pub ahead of print) In: The Lancet Microbe. Online first, 12 p., 100952.
Research output: Contribution to journal › Article › peer-review
Schlieren texture and topography induced confinement in an organic exciton-polariton laser
Le Roux, F., Mischok, A., Tenopala-Carmona, F. & Gather, M. C., 18 Jan 2025, In: Nature Communications. 16, 10 p., 811.
Research output: Contribution to journal › Article › peer-review
Sigmatropic rearrangement enables access to a highly stable spirocyclic nitroxide for protein spin labelling
Sowiński, M. P., Mocanu, E. M., Ruskin-Dodd, H., McKay, A. P., Cordes, D. B., Lovett, J. E. & Haugland-Grange, M., 27 Mar 2025, (E-pub ahead of print) In: Chemical Communications. Advance Article, 4 p.
Research output: Contribution to journal › Article › peer-review
Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody
Randall, R. E., Young, D. F., Pisliakova, M., Andrejeva, J., West, L., Rossler, L., Morath, V., Hughes, D. J. & Goodbourn, S., 9 Jan 2025, In: Journal of General Virology. 106, 1, 13 p.
Research output: Contribution to journal › Article › peer-review
Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11
Ravenhill, B. J., Oliveira, M., Wood, G., Di, Y., Kite, J., Wang, X., Davies, C. T. R., Lu, Y., Antrobus, R., Elliott, G., Irigoyen, N., Hughes, D. J., Lyons, P. A., Chung, B., Borner, G. H. H. & Weekes, M. P., 25 Feb 2025, In: Cell Reports. 44, 2, 21 p., 115263.
Research output: Contribution to journal › Article › peer-review
The effect of depth on the composition and saturation of total fatty acids present within the tissues and skeletons of two reef-building corals
von Xylander, N. S. H., Hedouin, L., Smith, T. K. & Allison, N., 1 May 2025, In: Marine Biology. 172, 5, 16 p., 65.
Research output: Contribution to journal › Article › peer-review
Data from
The University of St Andrews Research Portal.