Publications

3′-O-β-Glucosyl-4′,5′-didehydro-5′-deoxyadenosine Is a Natural Product of the Nucleocidin Producers Streptomyces virens and Streptomyces calvus
Clarke, D., Feng, X., Deng, H., Zhang, Q. & O'Hagan, D., 25 Sept 2023, (E-pub ahead of print) In: Journal of Natural Products.
Research output: Contribution to journal › Article › peer-review

4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics
Lowe, P. T. & O’Hagan, D., 7 Jan 2023, In: Chemical Society Reviews. 52, 1, p. 248-276 29 p.
Research output: Contribution to journal › Review article › peer-review

6 Does mitsugumin 23 play a role in doxorubicin-induced cardiotoxicity
Abraham, K., Dorward, A. M., Hurst, Q. & Pitt, S. J., 22 Mar 2023, In: Heart. 109, 2
Research output: Contribution to journal › Abstract › peer-review

Klebsiella pneumoniae carbapenamases in Escherichia coli isolated from humans and livestock in rural South-Western Uganda
Tuhamize, B., Asiimwe, B., Kassaza, K., Sabiiti, W., Holden, M. & Bazira, J., 13 Jul 2023, In: PLoS One. 18, 7, 10 p., e0288243.
Research output: Contribution to journal › Article › peer-review

A dissipative reaction network drives transient solid-liquid and liquid-liquid phase cycling of nanoparticles
Roy, S., Gravener, L., Philp, D. & Kay, E. R., 22 May 2023, In: Angewandte Chemie International Edition. 62, 22, 8 p., e202217613.
Research output: Contribution to journal › Article › peer-review

A new simple and effective method for PLRV infection to screen for virus resistance in potato
Cowan, G., MacFarlane, S. & Torrance, L., 20 Feb 2023, (E-pub ahead of print) In: Journal of Virological Methods. 315, 114691.
Research output: Contribution to journal › Article › peer-review

A practical approach to render tuberculosis samples safe for application of tuberculosis Molecular Bacterial Load Assay in clinical settings without a biosafety level 3 laboratory
Mtafya, B. A., Qwaray, P., John, J., Sichone, E., Shoo, A., Gillespie, S. H., Ntinginya, N. E. & Sabiiti, W., Jan 2023, In: Tuberculosis. 138, 5 p., 102275.
Research output: Contribution to journal › Article › peer-review

AAV9-mediated SMN gene therapy rescues cardiac desmin but not Lamin a/C and elastin dysregulation in Smn  2B/- spinal muscular atrophy mice
Brown, S. J., Šoltić, D., Synowsky, S. A., Shirran, S. L., Chilcott, E., Shorrock, H. K., Gillingwater, T. H., Yáñez-Muñoz, R. J., Schneider, B., Bowerman, M. & Fuller, H. R., 27 Jun 2023, (Accepted/In press) In: Human Molecular Genetics.
Research output: Contribution to journal › Article › peer-review

Activation of Csm6 ribonuclease by cyclic nucleotide by cyclic nucleotide binding: in an emergency twist to open
McQuarrie, S. J., Athukoralage, J. S., McMahon, S., Graham, S., Ackermann, K., Bode, B. E., White, M. & Gloster, T., 25 Sept 2023, (E-pub ahead of print) In: Nucleic Acids Research.
Research output: Contribution to journal › Article › peer-review

Adeno-associated virus 2 infection in children with non-A-E hepatitis
Ho, A., DIAMONDS consortium, ISARIC4C investigators, Willett, B. J., Breuer, J., Semple, M. G., Turner, D., Baillie, J. K. & Thomson, E. C., 30 Mar 2023, (E-pub ahead of print) In: Nature.
Research output: Contribution to journal › Article › peer-review

Allele distribution and phenotypic resistance to ciprofloxacin and gentamicin among extended spectrum β-lactamases producing Escherichia coli from urine, stool, animals and environments of patients with presumptive urinary tract infection in Tanzania
Mwakyoma, A. A., Kidenya, B. R., Minja, C. A., Mushi, M. F., Sandeman, A. F., Sabiiti, W., Holden, M. & Mshana, S. E., 5 Jun 2023, In: Frontiers in Antibiotics. 2, 11 p., 1164016.
Research output: Contribution to journal › Article › peer-review

An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa
Harding, C. J., Bischoff, M., Bergkessel, M. & Melo Czekster, C., 29 Jun 2023, (E-pub ahead of print) In: Nature Chemical Biology. 15 p.
Research output: Contribution to journal › Article › peer-review

An eggshell-localised annexin plays a key role in the coordination of the life cycle of a plant-parasitic nematode with its host
Price, J. A., Ali, M. F., Major, L. L., Smith, T. K. & Jones, J. T., 13 Feb 2023, In: PLoS Pathogens. 19, 2, 19 p., e1011147.
Research output: Contribution to journal › Article › peer-review

An electric molecular motor
Zhang, L., Qiu, Y., Liu, W-G., Chen, H., Shen, D., Song, B., Cai, K., Wu, H., Jiao, Y., Feng, Y., Seale, J. S. W., Pezzato, C., Tian, J., Tan, Y., Chen, X-Y., Guo, Q-H., Stern, C. L., Philp, D., Astumian, R. D., Goddard, W. A., & 1 othersStoddart, J. F., 12 Jan 2023, In: Nature. 613, 7943, p. 280-286 7 p.
Research output: Contribution to journal › Article › peer-review

An exciplex-based light-emission pathway for solution-state electrochemiluminescent devices
Moon, C-K., Butscher, J. F. & Gather, M. C., 25 Jul 2023, (E-pub ahead of print) In: Advanced Materials. Early View, 9 p., 2302544.
Research output: Contribution to journal › Article › peer-review

Antibiotic dispensing practices during COVID-19 and implications for antimicrobial resistance (AMR): parallel mystery client studies in Uganda and Tanzania
Olamijuwon, E., Konje, E., Kansiime, C., Kesby, M., Keenan, K., Neema, S., Asiimwe, B., Mshana, S. E., Mushi, M. F., Loza, O., Sunday, B., Sandeman, A., Sloan, D. J., Benitez-Paez, F., Mwanga, J. R., Sabiiti, W., Holden, M. T. G. & CARE Consortium, 11 Feb 2023, In: Antimicrobial Resistance & Infection Control. 12, 1, 14 p., 10.
Research output: Contribution to journal › Article › peer-review

Antibiotics under our feet
Cornwell, R. M., Melo Czekster, C., Gibeily, C., Ionescu, D., Harper, S., Kennedy, M., Sutherland, E. J., Simpson, M. C., Easton, E., Vaughan, R., Jones, C. E., Lynch, R., Yong, E., Athukoralage, J. S., Hogrel, G., Zickuhr, G. M., Hynes, J., Williams, R-J., Ross, K. S., Kruger, L., & 9 othersWoods, R. E., St Agatha's RC Primary School, Aberdour School, Getting Better Together Shotts, 8th Fife (St Andrews) Cub Scouts, St Andrews Botanic Garden, Nuffield Research Placements, Thornton Primary School & Greyfriars Primary School, St Andrews, 25 Apr 2023, Antibiotics under our feet.
Research output: Other contribution

Antiviral signaling by a cyclic nucleotide activated CRISPR protease
Rouillon, C. M. J., Schneberger, N., Chi, H., Blumenstock, K., Da Vela, S., Ackermann, K., Moecking, J., Peter, M. F., Boenigk, W., Seifert, R., Bode, B. E., Schmid-Burgk, J. L., Svergun, D., Geyer, M., White, M. & Hageluken, G., 2 Feb 2023, In: Nature. 614, p. 168–174
Research output: Contribution to journal › Article › peer-review

Aryl (β, β', β''-trifluoro)-tert-butyl: a candidate motif for the discovery of bioactives
O'Hagan, D., Cordes, D. B., Dobson, L., Oke, O. O., Zhang, Q., Cormanich, R., Isanbor, C., McKay, B., Khan, M. F., Piscelli, B. & Murphy, C., 22 Sept 2023, In: Organic Letters. 25, 37, 6802 p.
Research output: Contribution to journal › Article › peer-review

Assessing the impact of interfering organic matter on soil metaproteomic workflow
Waibel, M., McDonnell, K., Tuohy, M., Shirran, S., Synowsky, S., Thornton, B., Paterson, E., Brennan, F. & Abram, F., 22 Jun 2023, In: European Journal of Soil Science. 74, 3, 14 p., e13392.
Research output: Contribution to journal › Article › peer-review

Author Correction: Cyclic nucleotide-induced helical structure activates a TIR immune effector (Nature, (2022), 608, 7924, (808-812), 10.1038/s41586-022-05070-9)
Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L. & White, M. F., 2 Feb 2023, In: Nature. 614, 7946, p. E15
Research output: Contribution to journal › Comment/debate › peer-review

Bacterial etiology of urinary tract infections in patients treated at Kenyan health facilities and their resistance towards commonly used antibiotics
Kiiru, S., Maina, J., Katana, J., Mwaniki, J., Asiimwe, B. B., Mshana, S. E., Keenan, K., Gillespie, S. H., Stelling, J., Holden, M. T. G., Consortium, HATUA. & Kiiru, J., 26 May 2023, In: PLoS ONE. 18, 5, 14 p., e0277279.
Research output: Contribution to journal › Article › peer-review

Building sustainable clinical trial sites in Sub-Saharan Africa through networking, infrastructure improvement, training and conducting clinical studies: the PanACEA approach
Mekota, A-M., Gillespie, S. H., Hoelscher, M., Diacon, A. H., Dawson, R., Churchyard, G., Sanne, I., Minja, L., Kibiki, G., Maboko, L., Lakhi, S., Joloba, M., Alabi, A., Kirenga, B., McHugh, T. D., Grobusch, M. P. & Boeree, M. J., 1 Feb 2023, In: Acta Tropica. 238, 18 p., 106776.
Research output: Contribution to journal › Article › peer-review

CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM
Serra Lleti, J. M., Steyer, A. M., Schieber, N. L., Neumann, B., Tischer, C., Hilsenstein, V., Holtstrom, M., Unrau, D., Kirmse, R., Lucocq, J. M., Pepperkok, R. & Schwab, Y., 6 Mar 2023, In: Journal of Cell Biology. 222, 3, 26 p., e202209127.
Research output: Contribution to journal › Article › peer-review

Catalytic cycle of the bifunctional enzyme phosphoribosyl-ATP pyrophosphohydrolase/phosphoribosyl-AMP cyclohydrolase
Fisher, G., Pecaver, E., Read, B., Leese, S., Laing, E., Dickson, A., Melo Czekster, C. & da Silva, R. G., 2 Jun 2023, In: ACS Catalysis. 13, 11, p. 7669-7679 11 p.
Research output: Contribution to journal › Article › peer-review

Cell-to-cell connectivity assays for the analysis of cytoskeletal and other regulators of plasmodesmata
Barr, Z. & Tilsner, J., 12 Feb 2023, The plant cytoskeleton: methods and protocols. Hussey, P. J. & Wang, P. (eds.). New York, NY: Humana Press, p. 193-202 10 p. (Methods in molecular biology; vol. 2604).
Research output: Chapter in Book/Report/Conference proceeding › Chapter

Characterisation of arabinogalactan endo β 1,4 galactanases from Globodera rostochiensis, Globodera pallida and Rotylenchulus reniformis
Leslie, K., Mantelin, S., Eves-van den Akker, S. & Jones, J. T., 1 Jan 2023, In: Physiological and Molecular Plant Pathology. 123, 8 p., 101930.
Research output: Contribution to journal › Article › peer-review

Combination therapy with ciprofloxacin and pentamidine against Multidrug-Resistant Pseudomonas aeruginosa: assessment of in vitro and in vivo efficacy and the role of Resistance-Nodulation-Division (RND) efflux pumps
Fletcher, M., McCormack, A., Parcell, B. J. & Coote, P. J., 26 Jul 2023, In: Antibiotics. 12, 8, 18 p., 1236.
Research output: Contribution to journal › Article › peer-review

Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
Ayoun Alsoud, R., Svensson, R. J., Svensson, E. M., Gillespie, S. H., Boeree, M. J., Diacon, A. H., Dawson, R., Aarnoutse, R. E. & Simonsson, U. S. H., 14 Mar 2023, In: Frontiers in Pharmacology. 14, 12 p., 1067295.
Research output: Contribution to journal › Article › peer-review

Comparing ART outcomes in women with endometriosis after GnRH agonist versus GnRH antagonist ovarian stimulation: a systematic review
Kuan, K., Omoseni, S. & Tello, J. A., Dec 2023, In: Therapeutic Advances in Endocrinology and Metabolism. 14
Research output: Contribution to journal › Article › peer-review

Comparison of horizontal blaCTX-M gene transfer via conjugation among extended spectrum β-lactamases producing Escherichia coli isolates from patients with urinary tract infection, their animals and environment
Mwakyoma, A. A., Kidenya, B. R., Minja, C. A., Mushi, M. F., Sandeman, A., Sabiti, W., Holden, M. T. G. & Mshana, S. E., 22 May 2023, (E-pub ahead of print) In: Archives of Molecular Biology and Genetics. 2, 1, p. 1-8 8 p.
Research output: Contribution to journal › Article › peer-review

Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times
Sowiński, M. P., Gahlawat, S., Lund, B. A., Warnke, A-L., Hopmann, K. H., Lovett, J. E. & Haugland, M. M., 5 Jun 2023, In: Communications Chemistry. 6, 1, 8 p., 111.
Research output: Contribution to journal › Article › peer-review

Contribution of hyperconjugation and inductive effects to the pseudo-anomeric effect in 4-substituted methoxycyclohexanes
Piscelli, B. A., O’Hagan, D. & Cormanich, R. A., 26 Jan 2023, In: Journal of Physical Chemistry A. 127, 3, p. 724–728 5 p.
Research output: Contribution to journal › Article › peer-review

Cooling the optical-spin driven limit cycle oscillations of a levitated gyroscope
Arita, Y., Simpson, S., Bruce, G. D., Wright, E. M., cz, A. O. S. O. & Dholakia, K., 1 Sept 2023, (E-pub ahead of print) In: Communications Physics. 6
Research output: Contribution to journal › Article › peer-review

Cyclic dipeptides and the human microbiome: opportunities and challenges
Ogilvie, C. E. & Melo Czekster, C., 15 Jul 2023, In: Bioorganic & Medicinal Chemistry. 90, 6 p., 117372.
Research output: Contribution to journal › Review article › peer-review