Publications

A selection of recent BSRC members’ publications are listed below.

A genome-wide association study of Chinese and English language phenotypes in Hong Kong Chinese children
Lin, Y-P., Shi, Y., Zhang, R., Xue, X., Rao, S., Yin, L., Lui, K. F. H., Pan, D. J., Maurer, U., Choy, K-W., Paracchini, S., McBride, C. & So, H-C., 27 Mar 2024, In: npj Science of Learning. 9, 26, 18 p.
Research output: Contribution to journalArticlepeer-review

A highly stable and efficient organic microcavity polariton laser
Witt, J., Mischok, A., Le Roux, F. & Gather, M. C., 19 Mar 2024, (E-pub ahead of print) In: MRS Communications. 6 p.
Research output: Contribution to journalArticlepeer-review

Accuracy of the tuberculosis molecular bacterial load assay to diagnose and monitor response to anti-tuberculosis therapy: a longitudinal comparative study with standard-of-care smear microscopy, Xpert MTB/RIF Ultra, and culture in Uganda
Musisi, E., Wamutu, S., Ssengooba, W., Kasiinga, S., Sessolo, A., Sanyu, I., Kaswabuli, S., Zawedde, J., Byanyima, P., Kia, P., Muwambi, W., Toskin, D. T., Kigozi, E., Walbaum, N., Dombay, E., Legrady, M. B., Ssemambo, K. D-M., Joloba, M., Kuchaka, D., Worodria, W., & 3 othersHuang, L., Gillespie, S. H. & Sabiiti, W., Apr 2024, In: The Lancet Microbe. 5, 4, p. e345-e354
Research output: Contribution to journalArticlepeer-review

Allosteric activation unveils protein-mass modulation of ATP phosphoribosyltransferase product release
Read, B., Mitchell, J. B. O. & da Silva, R. G., 6 Apr 2024, In: Communications Chemistry. 7, 13 p., 77.
Research output: Contribution to journalArticlepeer-review

AtHVA22a, a plant-specific homologue of Reep/DP1/Yop1 family proteins is involved in turnip mosaic virus propagation
Xue, M., Sofer, L., Simon, V., Arvy, N., Diop, M., Lion, R., Beucher, G., Bordat, A., Tilsner, J., Gallois, J-L. & German-Retana, S., 20 May 2024, In: Molecular Plant Pathology. 25, 5, p. e13466
Research output: Contribution to journalArticlepeer-review

Bedaquiline-pretomanid-moxifloxacin-pyrazinamide for drug-sensitive and drug-resistant pulmonary tuberculosis treatment: a phase 2c, open-label, multicentre, partially randomised controlled trial
Cevik, M., Thompson, L. C., Upton, C., Rolla, V. C., Malahleha, M., Mmbaga, B., Ngubane, N., Abu Bakar, Z., Rassool, M., Variava, E., Dawson, R., Staples, S., Lalloo, U., Louw, C., Conradie, F., Eristavi, M., Samoilova, A., Skornyakov, S. N., Ntinginya, N. E., Haraka, F., & 28 othersPraygod, G., Mayanja-Kizza, H., Caoili, J., Balanag, V., Dalcolmo, M. P., McHugh, T., Hunt, R., Solanki, P., Bateson, A., Crook, A. M., Fabiane, S., Timm, J., Sun, E., Spigelman, M., Sloan, D. J., Gillespie, S. H., Bruinenberg, P., Beumont, M., Nedelman, J., Li, M., Zuma-Gwala, N., Rajaram, S., Choo, L., Wills, G., Betteridge, M., Leandra, L., Olugbosi, M. & Borisov, S., 17 May 2024, (E-pub ahead of print) In: The Lancet Infectious Diseases. In Press, 11 p.
Research output: Contribution to journalArticlepeer-review

Biogenesis, inheritance and 3D ultrastructure of the microsporidian mitosome
Hacker, C., Sendra, K., Keisham, P. D., Filipescu, T., Lucocq, J., Salimi, F., Ferguson, S. G. A., Bhella, D., MacNeill, S., Embley, M. & Lucocq, J. M., 1 Jan 2024, In: Life Science Alliance. 7, 1, 23 p., e202201635.
Research output: Contribution to journalArticlepeer-review

CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23
Grüschow, S., McQuarrie, S., Ackermann, K., McMahon, S., Bode, BE., Gloster, TM. & White, MF., 12 Apr 2024, In: Nucleic Acids Research. 52, 6, p. 2761-2775 15 p., gkae167.
Research output: Contribution to journalArticlepeer-review

Changes in fibrin clot properties in patients after Roux en-Y gastric bypass surgery
Abbas, K., Hierons, S. J., Pechlivani, N., Phoenix, F., Alexander, R., King, R., Ajjan, R. A. & Stewart, A. J., 29 Feb 2024, (E-pub ahead of print) In: Research and Practice in Thrombosis and Haemostasis. 8, 2, 8 p., e102361.
Research output: Contribution to journalArticlepeer-review

Characterisation and mapping of a Globodera pallida resistance derived from the wild potato species Solanum spegazzinii
Gartner, U., Armstrong, M. R., Sharma, S. K., Jones, J. T., Blok, V. C., Hein, I. & Bryan, G. J., 16 Apr 2024, (E-pub ahead of print) In: Theoretical and Applied Genetics. 137, 5
Research output: Contribution to journalArticlepeer-review

Characterising the HLA-I Immunopeptidome of plasma-derived extracellular vesicles in patients with melanoma
Boyne, C. M., Coote, A., Synowsky, S. A., Naden, A. B., Shirran, S. L. & Powis, S. J., Mar 2024, In: Journal of Extracellular Biology. 3, 3, 12 p., e146.
Research output: Contribution to journalArticlepeer-review

Conformational analysis explores the role of electrostatic non-classical CFHC hydrogen bonding interactions in selectively halogenated cyclohexanes
He, M., Piscelli, B., Cormanich, R. & O'Hagan, D., 5 Mar 2024, (E-pub ahead of print) In: The Journal of Organic Chemistry. 89, 6, p. 4009–4018 10 p.
Research output: Contribution to journalArticlepeer-review

Consideration of within-patient diversity highlights transmission pathways and antimicrobial resistance gene variability in vancomycin-resistant Enterococcus faecium
McHugh, M. P., Pettigrew, K. A., Taori, S., Evans, T. J., Leanord, A., Gillespie, S. H., Templeton, K. E. & Holden, M. T. G., Mar 2024, In: Journal of Antimicrobial Chemotherapy. 79, 3, p. 656-668 13 p., dkae023.
Research output: Contribution to journalArticlepeer-review

Crystal structure, steady-state and pre-steady-state kinetics of Acinetobacter baumannii ATP phosphoribosyltransferase
Read, B., Cadzow, A., Alphey, M. S., Mitchell, J. B. O. & da Silva, R. G., 16 Jan 2024, In: Biochemistry. 63, 2, p. 230-240 11 p.
Research output: Contribution to journalArticlepeer-review

Developing biomarkers assays to accelerate tuberculosis drug development: defining target product profiles
Gillespie, S. H., DiNardo, A. R., Georghiou, S. B., Sabiiti, W., Kohli, M., Panzner, U., Kontsevaya, I., Hittel, N., Stuyver, L. J., Tan, J. B., van Crevel, R., Lange, C., Nguyen, T. T. T., Heyckendorf, J., Ruhwald, M. & Heinrich, N., 9 May 2024, (E-pub ahead of print) In: The Lancet Microbe. In Press, 11 p.
Research output: Contribution to journalReview articlepeer-review

Evaluation of acenes as potential acceptors in thermally activated delayed fluorescence emitters and the promise of a phenoxazine–naphthalene emitter for OLEDs
Lee, O. S., Sharma, N., Matulaitis, T., Slawin, A. M. Z., Olivier, Y., Samuel, I. D. W., Gather, M. C. & Zysman-Colman, E., 28 Mar 2024, In: Journal of Materials Chemistry C. 12, 12, p. 4273-4286 14 p.
Research output: Contribution to journalArticlepeer-review

High-brightness blue polariton organic light-emitting diodes
Witt, J., Mischok, A., Tenopala Carmona, F., Hillebrandt, S., Butscher, J. F. & Gather, M. C., 15 Apr 2024, (E-pub ahead of print) In: ACS Photonics. 11, 5, p. 1844–1850 7 p.
Research output: Contribution to journalArticlepeer-review

Human 2'-deoxynucleoside 5'-phosphate N-hydrolase 1: the catalytic roles of Tyr24 and Asp80
Carberry, A. E., Devi, S., Harrison, D. J. & da Silva, R. G., 2 Apr 2024, In: ChemBioChem. 25, 7, 10 p., e202400047.
Research output: Contribution to journalArticlepeer-review

Monitoring the conformational ensemble and lipid environment of a mechanosensitive channel under cyclodextrin-induced membrane tension
Lane, B. J., Ma, Y., Yan, N., Wang, B., Ackermann, K., Karamanos, T. K., Bode, B. E. & Pliotas, C., 22 Mar 2024, (E-pub ahead of print) In: Structure.
Research output: Contribution to journalArticlepeer-review

Multi-layered genome defences in bacteria
Agapov, A., Baker, K. S., Bedekar, P., Bhatia, R. P., Blower, T. R., Brockhurst, M. A., Brown, C., Chong, C. E., Fothergill, J. L., Graham, S., Hall, J. PJ., Maestri, A., McQuarrie, S., Olina, A., Pagliara, S., Recker, M., Richmond, A., Shaw, S. J., Szczelkun, M. D., Taylor, T. B., & 5 othersvan Houte, S., Went, S. C., Westra, E. R., White, M. F. & Wright, R., Apr 2024, In: Current Opinion in Microbiology. 78, 102436.
Research output: Contribution to journalReview articlepeer-review

Optimizing the performance of single-cell ICP-MS for Fe and Zn determination in human umbilical vascular endothelial cells  
Leal, K. N. S., da Silva, A. B. S., Aragão, A. Z. B., Ramos, C. H. I., Stewart, A. J. & Arruda, M. A. Z., 6 May 2024, (Accepted/In press) In: Microchemical Journal. 202, 110696.
Research output: Contribution to journalArticlepeer-review

Predominance of multidrug-resistant bacteria causing urinary tract infections among symptomatic patients in East Africa: a call for action
Maldonado-Barragán, A., Mshana, S. E., Keenan, K., Ke, X., Gillespie, S. H., Stelling, J., Maina, J., Bazira, J., Muhwezi, I., Mushi, M. F., Green, D. L., Kesby, M., Lynch, A. G., Sabiiti, W., Sloan, D. J., Sandeman, A., Kiiru, J., Asiimwe, B. & Holden, M. T. G., Feb 2024, In: JAC-Antimicrobial Resistance. 6, 1, 11 p., dlae019.
Research output: Contribution to journalArticlepeer-review

Pulse dipolar electron paramagnetic resonance spectroscopy distance measurements at low nanomolar concentrations: the CuII-trityl case
Ackermann, K., Heubach, C., Schiemann, O. & Bode, B. E., 31 Jan 2024, (E-pub ahead of print) In: The Journal of Physical Chemistry Letters. 15, p. 1455-1461 7 p.
Research output: Contribution to journalArticlepeer-review

Rapid determination of antimicrobial susceptibility of Gram-negative bacteria from clinical blood cultures using a scattered light integrated collection (SLIC) device
Falconer, K., Hammond, R., Parcell, B. J. & Gillespie, S. H., 28 Feb 2024, In: Journal of Medical Microbiology. 73, 2, 11 p., 001812.
Research output: Contribution to journalArticlepeer-review

Recent advances in metalloproteomics
Coverdale, J. P. C., Polepalli, S., Arruda, M. A. Z., Santos Da Silva, A. B., Stewart, A. J. & Blindauer, C. A., 13 Jan 2024, In: Biomolecules. 14, 1, 31 p., 104.
Research output: Contribution to journalReview articlepeer-review

Repurposing mitomycin C in combination with pentamidine or gentamicin to treat infections with multi-drug resistant (MDR) 3 Pseudomonas aeruginosa
Svedholm, E. L., Bruce, B., Parcell, B. J. & Coote, P. J., 10 Feb 2024, In: Antibiotics. 13, 2, 15 p., 177.
Research output: Contribution to journalArticlepeer-review

Reversible conjugation of a CBASS nucleotide cyclase regulates bacterial immune response to phage infection
Kruger, L., Gaskell-Mew, L., Graham, S., Shirran, S. L., Hertel, R. & White, M., 8 Apr 2024, In: Nature Microbiology. 33 p.
Research output: Contribution to journalArticlepeer-review

Robust identification of interactions between heat-stress responsive genes in the chicken brain using Bayesian networks and augmented expression data
Videla Rodriguez, E. A., Mitchell, J. B. O. & Smith, V. A., 19 Apr 2024, In: Scientific Reports. 14, 8 p., 9019.
Research output: Contribution to journalArticlepeer-review

SARS-CoV-2 ORF8 as a modulator of cytokine induction: evidence and search for molecular mechanisms
Móvio, M. I., Carneiro, G., Lopes Martines, I. D. G., Barros de Lima, G., Sasaki, S. D., Kihara, A. H., Poole, E., Nevels, M. M. & Carlan de Silva, M. C., 22 Jan 2024, In: Viruses. 16, 1, 15 p., 161.
Research output: Contribution to journalReview articlepeer-review

Snapshots of the reaction coordinate of a thermophilic 2'-deoxyribonucleoside/ribonucleoside transferase
Tang, P., Harding, C. J., Dickson, A., da Silva, R. G., Harrison, D. J. & Melo Czekster, C., 1 Mar 2024, In: ACS Catalysis. 14, 5, p. 3090-3102 13 p.
Research output: Contribution to journalArticlepeer-review

The identification and heterologous expression of the biosynthetic gene cluster encoding the antibiotic and anticancer agent marinomycin
Abraham, E., Lawther, H., Wang, Y., Zarins-Tutt, J. S., Rivera, G. S., Wu, C. C., Connoly, J., Florence, G. J., Agbo, M. O., Gao, H. & Goss, R., 16 Jan 2024, In: Biomolecules. 14, 1, 11 p., 117.
Research output: Contribution to journalArticlepeer-review

The role of ion dissolution in metal and metal oxide surface inactivation of SARS CoV-2
Hilton, J. V., Nanao, Y., Flokstra, M. G., Askari, M., Smith, T. K., Di Falco, A., King, P., Wahl, P. & Adamson, C. S., Feb 2024, In: Applied and Environmental Microbiology. 90, 2, 15 p., e01553-23.
Research output: Contribution to journalArticlepeer-review

Topographic fingerprinting of single proteins and proteoforms
Penedo, C., 25 Mar 2024, In: Nature Nanotechnology.
Research output: Contribution to journalComment/debatepeer-review

Treatment seeking and antibiotic use for urinary tract infection symptoms in the time of COVID-19 in Tanzania and Uganda
Olamijuwon, E. O., Keenan, K. L., Mushi, M. F., Kansiime, C., Konje, E. T., Kesby, M., Neema, S., Asiimwe, B., Mshana, S. E., Fredricks, K. J., Sunday, B., Bazira, J., Sandeman, A. F., Sloan, D. J., Mwanga, J. R., Sabiiti, W., Holden, M. & CARE Consortium, 19 Jan 2024, (E-pub ahead of print) In: Journal of Global Health. 14, 10 p., 05007.
Research output: Contribution to journalArticlepeer-review

Treatment seeking behaviours, antibiotic use and relationships to multi-drug resistance: a study of urinary tract infection patients in Kenya, Tanzania and Uganda
Sado, K., Keenan, K., Manataki, A., Kesby, M., Mushi, M. F., Mshana, S. E., Mwanga, J. R., Neema, S., Asiimwe, B., Bazira, J., Kiiru, J., Green, D. L., Ke, X., Maldonado-Barragán, A., Abed Al Ahad, M., Fredricks, K. J., Gillespie, S. H., Sabiiti, W., Mmbaga, B. T., Kibiki, G., & 6 othersAanensen, D., Smith, V. A., Sandeman, A., Sloan, D. J., Holden, M. T. G. & Consortium, O. B. O. HATUA., 16 Feb 2024, In: PLOS Global Public Health. 4, 2, 20 p., e0002709.
Research output: Contribution to journalArticlepeer-review

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