Publications

A selection of recent BSRC members’ publications are listed below.

The catalytic enantioselective [1,2]-Wittig rearrangement cascade of allylic ethers
Kang, T., O'Yang, J., Kasten, K., Allsop, S. S., Lewis-Atwell, T., Farrar, E. H. E., Juhl, M., Cordes, D. B., McKay, A. P., Grayson, M. N. & Smith, A. D., 6 Jan 2026, (E-pub ahead of print) In: Nature Chemistry. AOP, 11 p.
Research output: Contribution to journalArticlepeer-review

Abnormal plasma/serum magnesium, copper and zinc concentrations associate with the future development of cardiovascular diseases
Lin, B., Alexander, R., Fritzen, R., Mills, S., Stewart, A. J. & McCowan, C., 25 Apr 2025, In: Nutrients. 17, 9, p. 1-14 14 p., 1447.
Research output: Contribution to journalArticlepeer-review

An updated evolutionary classification of CRISPR–Cas systems including rare variants
Makarova, K. S., Shmakov, S. A., Wolf, Y. I., Mutz, P., Altae-Tran, H., Beisel, C. L., Brouns, S. J. J., Charpentier, E., Cheng, D., Doudna, J., Haft, D. H., Horvath, P., Moineau, S., Mojica, F. J. M., Pausch, P., Pinilla-Redondo, R., Shah, S. A., Siksnys, V., Terns, M. P. & Tordoff, J. & 9 others, Venclovas, Č., White, M. F., Yakunin, A. F., Zhang, F., Garrett, R. A., Backofen, R., van der Oost, J., Barrangou, R. & Koonin, E. V., 6 Nov 2025, In: Nature Microbiology. p. 1-30 30 p.
Research output: Contribution to journalArticlepeer-review

A programmatic assessment of dolutegravir adverse events and discontinuations in Uganda
Laker Odongpiny, E. A., Nicol, M., Katana, E., Owori, J., Buzibye, A., Sedan, K., Kesby, M., Holden, M., Owarwo, N., Meya, D., Castelnuovo, B., Sloan, D. J. & Sekaggya, C., 24 Jan 2025, (E-pub ahead of print) In: HIV Medicine. Early View, 14 p.
Research output: Contribution to journalArticlepeer-review

A2A adenosine receptor agonists with last-step enzymatic 18F-labelling potential (fluorinase) for positron emission tomography (PET)
Charalambous, N., Schleidt, C., Liu, R., Heitman, L. H., Dall'Angelo, S., O'Hagan, D. & Lowe, P. T., 26 Dec 2025, (E-pub ahead of print) In: European Journal of Organic Chemistry. Early View, 8 p., e202501125.
Research output: Contribution to journalArticlepeer-review

A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4
Orzechowski, M. G., Hoikkala, V., Chi, H., McMahon, S., Gloster, T. & White, M., Nov 2025, In: Biochemical Journal. 482, 22, p. 1-13 13 p., BCJ20253271.
Research output: Contribution to journalArticlepeer-review

A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system
Reglinski, M., Hurst, Q. W., Williams, D. J., Gierlinski, M., Tegin Şahin, A., Mathers, K., Ostrowski, A., Bergkessel, M., Zachariae, U., Pitt, S. J. & Coulthurst, S. J., Dec 2025, In: EMBO Journal. 44, 23, p. 6892–6918 27 p.
Research output: Contribution to journalArticlepeer-review

Bacteria use a decoy defence molecule to set a trap for viruses
White, M. F., 1 Oct 2025, In: Nature. p. 1-2 2 p.
Research output: Contribution to journalComment/debatepeer-review

Bioactivity profiles of progressively ring-fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto-piperazines as antitrypanosome agents
He, M., Thomson, C. M., Thompson, D., Kuodis, V., Smith, T. K., Dall'Angelo, S. & O'Hagan, D., 3 Oct 2025, (E-pub ahead of print) In: ChemBioChem. Early View, 8 p., 2500384.
Research output: Contribution to journalArticlepeer-review

Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Sutherland, E., Harding, C. J., du Monceau de Bergendal, T., Florence, G. J., Ackermann, K., Bode, B. E., Synowsky, S., Sundaramoorthy, R. & Melo Czekster, C., 24 Jan 2025, In: Nature Communications. 16, 14 p., 995.
Research output: Contribution to journalArticlepeer-review

Building a cell-factory in Crithidia fasciculata: a bio-sustainable system to produce high-value polyunsaturated fatty acids
Cerone, M., Major, L. L. & Smith, T. K., 23 Jun 2025, In: Microbial Cell Factories. 24, p. 1-16 16 p., 142.
Research output: Contribution to journalArticlepeer-review

Cardiac safety of bedaquiline, delamanid and moxifloxacin co-administered with or without varying doses of sutezolid or delpazolid for the treatment of drug-susceptible TB
Koele, S. E., Stoycheva, K., Mtweve, C., Manyama, C., Mpagama, S., Mhimbira, F., Wallis, R., Ntinginya, N. E., Liyoyo, A., Huglin, B., Minja, L. T., Wagnerberger, L., Zumba, T., Noreña, I., Peter, D. D., Beattie, T., Makkan, H., Sloan, D. J., Te Brake, L. & Aarnoutse, R. E. & 9 others, McHugh, T. D., Wildner, L., Schildkraut, J., Aldana, B. H., Phillips, P. P. J., Hoelscher, M., Svensson, E. M., Heinrich, N. & PanACEA Consortium, Aug 2025, In: Journal of Antimicrobial Chemotherapy. 80, 8, p. 2305-2313 9 p.
Research output: Contribution to journalArticlepeer-review

Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomiasis
Gruschow, S., Steketee, P. C., Paxton, E., Matthews, K. R., Morrison, L. J., White, M. F. & Grey, F., 17 Mar 2025, In: PLoS Neglected Tropical Diseases. 19, 3, p. 1-17 17 p., e0012937.
Research output: Contribution to journalArticlepeer-review

Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomosis
Grüschow, S., Steketee, P. C., Paxton, E., Matthews, K. R., Morrison, L. J., White, M. F. & Grey, F., 17 Mar 2025, In: PLoS Neglected Tropical Diseases. 19, 3, p. 1-17 17 p., e0012937.
Research output: Contribution to journalArticlepeer-review

Characterising PMP22 proximal partners in a Schwann cell model of Charcot-Marie-Tooth disease type1A
Holt, I., Emery, N., Gates, M. A., Brown, S. J., Shirran, S. & Fuller, H. R., 5 Nov 2025, In: Biology. 14, 11, p. 1-32 32 p., 1552.
Research output: Contribution to journalArticlepeer-review

Chiral molecular 4f qubits by post functionalization
Hansen, S. H., Buch, C. D., Bode, B. E. & Piligkos, S., 21 Dec 2025, In: Inorganic Chemistry Frontiers . 12, 24, p. 8000-8007 8 p.
Research output: Contribution to journalArticlepeer-review

Clinical standards for antimicrobial stewardship in TB care
Brehm, T. T., Akkerman, O. W., Sotgiu, G., Tiberi, S., Chang, K.-C., Dheda, K., Duarte, R., Vambe, D., Udwadia, Z. F., Chesov, D., Mendelson, M., Iswari Saktiawati, A. M., van Ingen, J., Eyuboglu, F. O., Tängdén, T., Quang Vo, L. N., Riccardi, N., Moschos, C., Friedland, J. S. & Lillebaek, T. & 40 others, Chandy, S. J., Caminero, J. A., Thwaites, G., Gandra, S., Thursky, K., George, I. A., Konstantynovska, O., Fatima, R., Yim, J.-J., Kwak, N., Olaru, I. D., Gillespie, S. H., Kherabi, Y., Perl, S. H., Grønningen, E., Rodrigues, C., Bjerrum, S., Bange, F., Cox, V., Cirillo, D. M., Saluzzo, F., Hara, G. L., Wagner, D., Ismail, N., Sloan, D. J., Eshun-Wilsonova, I., Zeng, M., Cantero, C., Vasankari, T., Mandalakas, A., Kay, A., Ness, T., Torrico, M. M., Günther, G., Kuksa, L., Guglielmetti, L., García-Basteiro, A. L., Marks, G. B., Pulcini, C. & Lange, C., 10 Dec 2025, In: IJTLD open. 2, 12, p. 716-726 11 p.
Research output: Contribution to journalArticlepeer-review

Competitive behaviors in Serratia marcescens are coordinately regulated by a lifestyle switch frequently inactivated in the clinical environment
Williams, D. J., Hawkins, A., Hernandez, R. E., Mariano, G., Mathers, K., Buchanan, G., Stonier, B. J., Inkster, T., Leanord, A., Chalmers, J. D., Thomson, N. R., Holden, M. T. G. & Coulthurst, S. J., 12 Feb 2025, In: Cell Host & Microbe. 33, 2, p. 252-266.E5 20 p.
Research output: Contribution to journalArticlepeer-review

Conference report: The second bacterial genome sequencing Pan-European Network conference
Wei, K. C., Purushothaman, S., Azzato, F., Baker, K. S., Birkeland, K. W., Brunet, S., Campos, J., Connor, T. R., Giske, C. G., Greub, G., Hallbäck, E. T., Harmsen, D., Hodcroft, E. B., Holden, M. T. G., Jacob, J., Kahles, A., Lagos, A. C., Lipworth, S., Loo, E. & Miotto, P. & 15 others, Neher, R. A., Neves, A., Ready, D., Roloff, T., Rooney, A., Rousseau, E., Schrenzel, J., Sundqvist, M., Viegas, S., Wegner, F., Aamot, H. V., Niemann, S., Williamson, D. A., Mölling, P. & Egli, A., 23 Oct 2025, In: Microbes and Infection. 27, 7, p. 1-8 8 p., 105557.
Research output: Contribution to journalArticlepeer-review

CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes
Sun, Y., Kronenberg, N. M., Sethi, S. K., Dash, S. N., Kovalik, M. E., Sempowski, B., Strickland, S., Raina, R., Sperati, C. J., Tian, X., Ishibe, S., Hall, G. & Gather, M. C., 1 Apr 2025, In: American Journal of Physiology - Renal Physiology. 328, 4, p. F578-F595 18 p.
Research output: Contribution to journalArticlepeer-review

Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin
Ishimoto, N., Wong, J. L. C., He, S., Shirran, S., Wright-Paramio, O., Seddon, C., Singh, N., Balsalobre, C., Sonani, R. R., Clements, A., Egelman, E. H., Frankel, G. & Beis, K., 22 Apr 2025, In: Proceedings of the National Academy of Sciences. 122, 16, p. 1-8 8 p., e2427228122.
Research output: Contribution to journalArticlepeer-review

Cycloadditions as a sweet route to ‘double C-glycosylation’
Mahoney, K. P. P., Lynch, R., Bown, R. T., Sharma, S. V., Chueakwon, P., Stephenson, G. R., Cordes, D. B., Slawin, A. M. Z. & Goss, R., 19 Jun 2025, In: Biomolecules. 15, 6, 905.
Research output: Contribution to journalArticlepeer-review

Data transparency and reproducibility in health research: bridging the gap for early-career researchers
Bhakta, S., Xie, J., Pea, F. & Gillespie, S. H., 29 Apr 2025, In: Frontiers in Antibiotics. 4, p. 1-6 6 p., 1562002.
Research output: Contribution to journalArticlepeer-review

Diversity and abundance of ring nucleases in type III CRISPR-Cas loci
Hoikkala, V., Chi, H., Grüschow, S., Graham, S. & White, M. F., 4 Sept 2025, In: Proceedings of the Royal Society B: Biological Sciences. 380, 1934, p. 1-8 8 p., 20240084.
Research output: Contribution to journalArticlepeer-review

DNA sensing with whispering gallery mode microlasers
Caixero, S., Dörrenhaus, R., Popczyk, A., Schubert, M., Kath-Schorr, S. & Gather, M. C., 19 Mar 2025, In: Nano Letters. 25, 11, p. 4467–4475
Research output: Contribution to journalLetterpeer-review

Enantiocontrol in radical coupling reactions: a catalytic [1,2]-rearrangement of allylic ammonium ylides
Hartley, W., Kasten, K. & Smith, A. D., 3 Nov 2025, (E-pub ahead of print) In: Synlett. eFirst, 7 p.
Research output: Contribution to journalArticlepeer-review

Engineering mechanical resonances of magnetoelectric transducers
Butscher, J. F. & Gather, M. C., 4 Feb 2025, In: Applied Physics Letters. 126, 5, 6 p., 053503.
Research output: Contribution to journalArticlepeer-review

Estimating full-field displacement in biological images using deep learning
Warsop, S. J. E. T., Caixeiro , S., Bischoff, M., Kursawe, J., Bruce, G. D. & Wijesinghe, P., 4 Jun 2025, In: npj Artificial Intelligence. 1, 12 p., 6.
Research output: Contribution to journalArticlepeer-review

Experimental analysis to quantify inactivation of microorganisms by Far-UVC irradiation in indoor environments
Hiwar, W., Adamson, C. S., Brenner, D. J., Fletcher, L. A., King, M.-F., McQuaid, J. B., Tidswell, E., Noakes, C. J., Wood, K. & Eadie, E., 15 Apr 2025, In: Building and Environment. 274, p. 1-10 10 p., 112734.
Research output: Contribution to journalArticlepeer-review

Exploring linear mono-, bis- and tris-acetylene containing agonists of the human olfactory receptor OR1A1
Liu, W., Dobson, L. S., Zhang, C., Sun, J., Lowe, P. T., Liu, Y., Zhuang, H. & O'Hagan, D., 16 Jun 2025, (E-pub ahead of print) In: Journal of Medicinal Chemistry. Ahead of Print, 11 p.
Research output: Contribution to journalArticlepeer-review

Exploring the activity of the putative Δ6-desaturase and its role in bloodstream form life-cycle transitions in Trypanosoma brucei
Cerone, M. & Smith, T. K., 18 Feb 2025, In: PLoS Pathogens. 21, 2, p. 1-39 39 p., e1012691.
Research output: Contribution to journalArticlepeer-review

Expression profile of human cytomegalovirus UL111A cmvIL-10 and LAcmvIL-10 transcripts in primary cells and cells from renal transplant recipients
Almeida, G. W. C., Oliveira, M. T., Martines, I. G. L., Fiori, G. C., Nevels, M. M., Groves, I. J., Sinclair, J., Medina-Pestana, J., Sampaio da Silva, R., Nakamura, M., Requião-Moura, L., Poole, E. & Carlan da Silva, M. C., 31 Mar 2025, In: Viruses. 17, 15 p., 501.
Research output: Contribution to journalArticlepeer-review

From oxygen to tellurium: the impact of the chalcogen on nucleophilicities and basicities of isochalcogenourea catalysts
Stockhammer, L., Kasten, K., Eitzinger, A., Vogl, L. S., Piringer, M., Weinzierl, D., Ofial, A. R., Smith, A. D. & Waser, M., 23 Oct 2025, (E-pub ahead of print) In: Angewandte Chemie International Edition. Early View, 15 p., e202514865.
Research output: Contribution to journalArticlepeer-review

FXR activation aids fibrinolysis: targeting PAI-1 in obesity
Stewart, A. J., 13 Nov 2025, In: Blood. 146, 20, p. 2381-2382 2 p.
Research output: Contribution to journalComment/debatepeer-review

Genetics of human handedness: microtubules and beyond
Ocklenburg, S., Mundorf, A., Peterburs, J. & Paracchini, S., Jun 2025, In: Trends in Genetics. 41, 6, p. 497-505 9 p.
Research output: Contribution to journalReview articlepeer-review

Data from
The University of St Andrews Research Portal.