Publications
A selection of recent BSRC members’ publications are listed below.
An active matter model captures spatial dynamics of actomyosin oscillations in larval epithelial cells during Drosophila morphogenesis
Mackay, E., Bebbington, A., Januschke, J., Kursawe, J., Bischoff, M. & Sknepnek, R., 20 Jan 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 3, p. 1-12 12 p., e2503955123.
Research output: Contribution to journal › Article › peer-review
A pragmatic trial with an optimized dose of rifampicin and moxifloxacin for the treatment of drug-susceptible pulmonary tuberculosis: a study protocol for open-label, randomized phase III trial (OptiRiMoxTB)
Mlyuka, H. J., Liyoyo, A., Nyaulingo, B., Mpolya, E., Kaswaga, O. L., Semvua, H., Lwambura, S., McHugh, T. D., Wildner, L., Sabiiti, W., Adegbite, B. R., Nliwasa, M., Khosa, C., Mbelele, P., Mbeya, B., Jeremiah, K., Boeree, M. J., Gillespie, S. H., Sloan, D. J. & Mpagama, S. G. & 1 others, , 30 Jan 2026, (E-pub ahead of print) In: Trials. p. 1-35 35 p.
Research output: Contribution to journal › Article › peer-review
Harnessing the orientation of columnar discotic liquid crystals for narrowband blue emission with enhanced out-coupling efficiency toward improvement of SP-OLEDs performance
De, J., Gupta, A. K., Litvinas, D., Tenopala-Carmona, F., Lehmann, M., Gather, M. C. & Zysman-Colman, E., 7 Feb 2026, (E-pub ahead of print) In: Advanced Functional Materials. Early View, 14 p., e28081.
Research output: Contribution to journal › Article › peer-review
High-power pulsed electrochemiluminescence for optogenetic manipulation of Drosophila larval behaviour
Moon, C.-K., König, M., Sircar, R., Butscher, J. F., Alle, R., Meerholz, K., Pulver, S. R. & Gather, M. C., 5 Feb 2026, In: Light: Science & Applications. 15, 11 p., 104.
Research output: Contribution to journal › Article › peer-review
Knockout of the intracellular calcium conducting ion channel Mitsugumin 23 (MG23) protects against pressure overload induced left ventricular hypertrophy and cardiac dysfunction
Dorward, A. M., Robertson, G. B., Sneddon, C., Edel, R. C., O'Rourke, C. L., Um, I. H., Harrison, D. J., Nishi, M., Takeshima, H., Murdoch, C. E. & Pitt, S. J., 31 Jan 2026, In: FASEB Journal. 40, 2, p. 1-16 16 p., e71440.
Research output: Contribution to journal › Article › peer-review
Should I stay or should I go – does protein localisation to plasmodesmata depend on targeting signals?
Barr, Z. K. & Tilsner, J., 27 Jan 2026, In: Journal of Experimental Botany. 77, 3, p. 692–696 5 p., eraf278.
Research output: Contribution to journal › Review article › peer-review
Structure and mechanism of the broad spectrum CRISPR-associated ring nuclease Crn4
Chi, H., Hoikkala, V., McMahon, S., Graham, S., Gloster, T. & White, M., 23 Jan 2026, In: Nature Communications. 17, p. 1-10 10 p., 889.
Research output: Contribution to journal › Article › peer-review
Students as carbon accountants: calculating carbon costs of a PhD in neuroscience
Smith, W. V., Bebbington, A., Sircar, R., Gather, M. & Pulver, S., 1 Feb 2026, In: Genetics. 232, 2, iyaf268.
Research output: Contribution to journal › Article › peer-review
The catalytic enantioselective [1,2]-Wittig rearrangement cascade of allylic ethers
Kang, T., O'Yang, J., Kasten, K., Allsop, S. S., Lewis-Atwell, T., Farrar, E. H. E., Juhl, M., Cordes, D. B., McKay, A. P., Grayson, M. N. & Smith, A. D., 6 Jan 2026, (E-pub ahead of print) In: Nature Chemistry. AOP, 11 p.
Research output: Contribution to journal › Article › peer-review
Toward an improved understanding of dyslexia: reflections on a new consensus definition and its implications
Morsanyi, K., Paracchini, S., Krishnan, S., Manning, C., Milne, J., Van Herwegen, J. & Luciano, M., Feb 2026, In: Dyslexia. 32, 1, p. 1-9 9 p., e70022.
Research output: Contribution to journal › Comment/debate › peer-review
Abnormal plasma/serum magnesium, copper and zinc concentrations associate with the future development of cardiovascular diseases
Lin, B., Alexander, R., Fritzen, R., Mills, S., Stewart, A. J. & McCowan, C., 25 Apr 2025, In: Nutrients. 17, 9, p. 1-14 14 p., 1447.
Research output: Contribution to journal › Article › peer-review
An updated evolutionary classification of CRISPR–Cas systems including rare variants
Makarova, K. S., Shmakov, S. A., Wolf, Y. I., Mutz, P., Altae-Tran, H., Beisel, C. L., Brouns, S. J. J., Charpentier, E., Cheng, D., Doudna, J., Haft, D. H., Horvath, P., Moineau, S., Mojica, F. J. M., Pausch, P., Pinilla-Redondo, R., Shah, S. A., Siksnys, V., Terns, M. P. & Tordoff, J. & 9 others, , 6 Nov 2025, In: Nature Microbiology. p. 1-30 30 p.
Research output: Contribution to journal › Article › peer-review
A programmatic assessment of dolutegravir adverse events and discontinuations in Uganda
Laker Odongpiny, E. A., Nicol, M., Katana, E., Owori, J., Buzibye, A., Sedan, K., Kesby, M., Holden, M., Owarwo, N., Meya, D., Castelnuovo, B., Sloan, D. J. & Sekaggya, C., 24 Jan 2025, (E-pub ahead of print) In: HIV Medicine. Early View, 14 p.
Research output: Contribution to journal › Article › peer-review
A2A adenosine receptor agonists with last-step enzymatic 18F-labelling potential (fluorinase) for positron emission tomography (PET)
Charalambous, N., Schleidt, C., Liu, R., Heitman, L. H., Dall'Angelo, S., O'Hagan, D. & Lowe, P. T., 26 Dec 2025, (E-pub ahead of print) In: European Journal of Organic Chemistry. Early View, 8 p., e202501125.
Research output: Contribution to journal › Article › peer-review
A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4
Orzechowski, M. G., Hoikkala, V., Chi, H., McMahon, S., Gloster, T. & White, M., Nov 2025, In: Biochemical Journal. 482, 22, p. 1-13 13 p., BCJ20253271.
Research output: Contribution to journal › Article › peer-review
A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system
Reglinski, M., Hurst, Q. W., Williams, D. J., Gierlinski, M., Tegin Şahin, A., Mathers, K., Ostrowski, A., Bergkessel, M., Zachariae, U., Pitt, S. J. & Coulthurst, S. J., Dec 2025, In: EMBO Journal. 44, 23, p. 6892–6918 27 p.
Research output: Contribution to journal › Article › peer-review
Bacteria use a decoy defence molecule to set a trap for viruses
White, M. F., 1 Oct 2025, In: Nature. p. 1-2 2 p.
Research output: Contribution to journal › Comment/debate › peer-review
Bioactivity profiles of progressively ring-fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto-piperazines as antitrypanosome agents
He, M., Thomson, C. M., Thompson, D., Kuodis, V., Smith, T. K., Dall'Angelo, S. & O'Hagan, D., 3 Oct 2025, (E-pub ahead of print) In: ChemBioChem. Early View, 8 p., 2500384.
Research output: Contribution to journal › Article › peer-review
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Sutherland, E., Harding, C. J., du Monceau de Bergendal, T., Florence, G. J., Ackermann, K., Bode, B. E., Synowsky, S., Sundaramoorthy, R. & Melo Czekster, C., 24 Jan 2025, In: Nature Communications. 16, 14 p., 995.
Research output: Contribution to journal › Article › peer-review
Building a cell-factory in Crithidia fasciculata: a bio-sustainable system to produce high-value polyunsaturated fatty acids
Cerone, M., Major, L. L. & Smith, T. K., 23 Jun 2025, In: Microbial Cell Factories. 24, p. 1-16 16 p., 142.
Research output: Contribution to journal › Article › peer-review
Cardiac safety of bedaquiline, delamanid and moxifloxacin co-administered with or without varying doses of sutezolid or delpazolid for the treatment of drug-susceptible TB
Koele, S. E., Stoycheva, K., Mtweve, C., Manyama, C., Mpagama, S., Mhimbira, F., Wallis, R., Ntinginya, N. E., Liyoyo, A., Huglin, B., Minja, L. T., Wagnerberger, L., Zumba, T., Noreña, I., Peter, D. D., Beattie, T., Makkan, H., Sloan, D. J., Te Brake, L. & Aarnoutse, R. E. & 9 others, , Aug 2025, In: Journal of Antimicrobial Chemotherapy. 80, 8, p. 2305-2313 9 p.
Research output: Contribution to journal › Article › peer-review
Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomiasis
Gruschow, S., Steketee, P. C., Paxton, E., Matthews, K. R., Morrison, L. J., White, M. F. & Grey, F., 17 Mar 2025, In: PLoS Neglected Tropical Diseases. 19, 3, p. 1-17 17 p., e0012937.
Research output: Contribution to journal › Article › peer-review
Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomosis
Grüschow, S., Steketee, P. C., Paxton, E., Matthews, K. R., Morrison, L. J., White, M. F. & Grey, F., 17 Mar 2025, In: PLoS Neglected Tropical Diseases. 19, 3, p. 1-17 17 p., e0012937.
Research output: Contribution to journal › Article › peer-review
Characterising PMP22 proximal partners in a Schwann cell model of Charcot-Marie-Tooth disease type1A
Holt, I., Emery, N., Gates, M. A., Brown, S. J., Shirran, S. & Fuller, H. R., 5 Nov 2025, In: Biology. 14, 11, p. 1-32 32 p., 1552.
Research output: Contribution to journal › Article › peer-review
Chiral molecular 4f qubits by post functionalization
Hansen, S. H., Buch, C. D., Bode, B. E. & Piligkos, S., 21 Dec 2025, In: Inorganic Chemistry Frontiers . 12, 24, p. 8000-8007 8 p.
Research output: Contribution to journal › Article › peer-review
Clinical standards for antimicrobial stewardship in TB care
Brehm, T. T., Akkerman, O. W., Sotgiu, G., Tiberi, S., Chang, K.-C., Dheda, K., Duarte, R., Vambe, D., Udwadia, Z. F., Chesov, D., Mendelson, M., Iswari Saktiawati, A. M., van Ingen, J., Eyuboglu, F. O., Tängdén, T., Quang Vo, L. N., Riccardi, N., Moschos, C., Friedland, J. S. & Lillebaek, T. & 40 others, , 10 Dec 2025, In: IJTLD open. 2, 12, p. 716-726 11 p.
Research output: Contribution to journal › Article › peer-review
Competitive behaviors in Serratia marcescens are coordinately regulated by a lifestyle switch frequently inactivated in the clinical environment
Williams, D. J., Hawkins, A., Hernandez, R. E., Mariano, G., Mathers, K., Buchanan, G., Stonier, B. J., Inkster, T., Leanord, A., Chalmers, J. D., Thomson, N. R., Holden, M. T. G. & Coulthurst, S. J., 12 Feb 2025, In: Cell Host & Microbe. 33, 2, p. 252-266.E5 20 p.
Research output: Contribution to journal › Article › peer-review
Conference report: The second bacterial genome sequencing Pan-European Network conference
Wei, K. C., Purushothaman, S., Azzato, F., Baker, K. S., Birkeland, K. W., Brunet, S., Campos, J., Connor, T. R., Giske, C. G., Greub, G., Hallbäck, E. T., Harmsen, D., Hodcroft, E. B., Holden, M. T. G., Jacob, J., Kahles, A., Lagos, A. C., Lipworth, S., Loo, E. & Miotto, P. & 15 others, , 23 Oct 2025, In: Microbes and Infection. 27, 7, p. 1-8 8 p., 105557.
Research output: Contribution to journal › Article › peer-review
CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes
Sun, Y., Kronenberg, N. M., Sethi, S. K., Dash, S. N., Kovalik, M. E., Sempowski, B., Strickland, S., Raina, R., Sperati, C. J., Tian, X., Ishibe, S., Hall, G. & Gather, M. C., 1 Apr 2025, In: American Journal of Physiology - Renal Physiology. 328, 4, p. F578-F595 18 p.
Research output: Contribution to journal › Article › peer-review
Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin
Ishimoto, N., Wong, J. L. C., He, S., Shirran, S., Wright-Paramio, O., Seddon, C., Singh, N., Balsalobre, C., Sonani, R. R., Clements, A., Egelman, E. H., Frankel, G. & Beis, K., 22 Apr 2025, In: Proceedings of the National Academy of Sciences. 122, 16, p. 1-8 8 p., e2427228122.
Research output: Contribution to journal › Article › peer-review
Cycloadditions as a sweet route to ‘double C-glycosylation’
Mahoney, K. P. P., Lynch, R., Bown, R. T., Sharma, S. V., Chueakwon, P., Stephenson, G. R., Cordes, D. B., Slawin, A. M. Z. & Goss, R., 19 Jun 2025, In: Biomolecules. 15, 6, 905.
Research output: Contribution to journal › Article › peer-review
Data transparency and reproducibility in health research: bridging the gap for early-career researchers
Bhakta, S., Xie, J., Pea, F. & Gillespie, S. H., 29 Apr 2025, In: Frontiers in Antibiotics. 4, p. 1-6 6 p., 1562002.
Research output: Contribution to journal › Article › peer-review
Diversity and abundance of ring nucleases in type III CRISPR-Cas loci
Hoikkala, V., Chi, H., Grüschow, S., Graham, S. & White, M. F., 4 Sept 2025, In: Proceedings of the Royal Society B: Biological Sciences. 380, 1934, p. 1-8 8 p., 20240084.
Research output: Contribution to journal › Article › peer-review
DNA sensing with whispering gallery mode microlasers
Caixero, S., Dörrenhaus, R., Popczyk, A., Schubert, M., Kath-Schorr, S. & Gather, M. C., 19 Mar 2025, In: Nano Letters. 25, 11, p. 4467–4475
Research output: Contribution to journal › Letter › peer-review
Enantiocontrol in radical coupling reactions: a catalytic [1,2]-rearrangement of allylic ammonium ylides
Hartley, W., Kasten, K. & Smith, A. D., 3 Nov 2025, (E-pub ahead of print) In: Synlett. eFirst, 7 p.
Research output: Contribution to journal › Article › peer-review
Data from
The University of St Andrews Research Portal.